Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00306Budesonide0.007110%
BADD_D00308Bupivacaine0.000788%
BADD_D00310Buprenorphine--
BADD_D00311Buprenorphine hydrochloride--
BADD_D00312Bupropion--
BADD_D00313Bupropion hydrobromide--
BADD_D00314Bupropion hydrochloride--
BADD_D00318Busulfan--
BADD_D00324Butorphanol--
BADD_D00325Butorphanol tartrate--
BADD_D00328Cabazitaxel--
BADD_D00329Cabergoline--
BADD_D00330Cabozantinib0.006660%
BADD_D00335Calcitonin--
BADD_D00336Calcitonin (salmon)--
BADD_D00344Canagliflozin--
BADD_D00346Candesartan--
BADD_D00347Candesartan cilexetil0.026984%
BADD_D00349Capecitabine--
BADD_D00353Capsaicin--
BADD_D00354Captopril0.003353%
BADD_D00356Carbamazepine0.015155%
BADD_D00359Carbidopa--
BADD_D00364Carboplatin0.020247%
BADD_D00365Carboprost--
BADD_D00366Carboprost tromethamine--
BADD_D00367Carfilzomib0.011456%
BADD_D00369Cariprazine--
BADD_D00374Carvedilol--
BADD_D00375Carvedilol phosphate--
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